NewsLetter

Need for an alternative preservative

In recent times, phenoxyethanol, a widely used preservative, has been found unsuitable for sensitive skin, as it is known to cause irritation. This may result in redness, itching, or a burning sensation. Cumulative exposure through multiple products can also cause a drying effect, further aggravating skin sensitivity. As a result, consumers with sensitive skin often seek alternatives or prefer formulations with lower concentrations to reduce the risk of adverse reactions.

Saliguard LAG as an ideal alternative to conventional preservatives

Saliguard LAG emerges as a promising solution in cosmetic preservation, marking a new era of efficacy and consumer-centric innovation. This preservative is an advanced blend of lactic acid, gluconolactone, and 1,2-hexanediol, designed to deliver multifunctional benefits that extend beyond traditional standards.

Unlike conventional preservatives, Saliguard LAG is free from phenoxyethanol, parabens, formaldehyde, and MIT/CMIT. It offers a clean, conscious, and biodegradable option, aligning with the growing demand for efficacious yet environmentally responsible preservative systems. For formulators, Saliguard LAG provides a skin-friendly, skin-compatible, and reliable preservation system.

Benefits over traditional preservative

The unique combination of lactic acid, gluconolactone, and 1,2-hexanediol in Saliguard LAG creates a synergistic approach to product preservation, setting a new benchmark for performance.

Beyond preservation, Saliguard LAG:

• • Regulates pH
• • Enhances formulation stability
• • Contributes to cosmetic elegance

Its broad-spectrum efficacy against bacteria and fungi ensures microbiological safety while meeting the rising demand for natural and multifunctional ingredients. Additionally, lactic acid and gluconolactone provide robust antimicrobial protection coupled with gentle exfoliation, creating a balanced, skin-compatible effect.

Saliguard LAG: Compatibility, Stability and Optimal pH

• • Dynamic Composition: The combination of gluconolactone and lactic acid enhances both the texture and tone of formulations.
• • Zero Impact on Consistency: No changes in color or viscosity, ensuring the purity of the finished product.
• • Compliant & Stable: Meets ISO standards with proven temperature stability between 50°C and 60°C.
• • Ease of Use: Can be incorporated into formulations below 60°C, providing flexibility in skincare product development.
• • Tested for Reliability: Extensive testing across various use levels and pH conditions (from 3 up to 6) confirms its effectiveness at 0.5% to 2.0% concentration, with optimal performance at pH ≤ 6.

Saliguard LAG: Technical Information

Saliguard LAG Formulations

Procedure:

1. Weigh ingredients of phase A in the main vessel. Heat up to 70 ° C.

2. Weigh all phase B ingredients in other Beaker. Heat up to 70 ° C.

3. Add phase B in phase A with continuous mixing.

4. Add phase C at 40° C and mix it well.

Appearance: Milky white cream

pH: 3.0

Challenge test results:

Inference: Saliguard LAG in the face cream showed broad-spectrum antimicrobial action—achieving >5 log reductions in bacteria (E.coli, P.aeruginosa, S.aureus) and fungi (C.albicans, A.niger) by Day 14. These reductions were sustained through Day 28, confirming preservative effectiveness.

Procedure:

1. Weigh ingredients of phase A in the main vessel. Heat up to 70° C.

2. Weigh all phase B ingredients in other Beaker and heat up to 70° C.

3. Then add phase B in Phase A with continuous mixing.

4. Add phase c at 40° C and mix it well.

Appearance: Milky White Lotion

pH: 5.5

Challenge test results:

Inference: In the tested body lotion formulation, Saliguard LAG achieved rapid and complete antimicrobial protection, with >5 log reductions for E.coli, P.aeruginosa, S.aureus, C.albicans, and A.brasiliensis by Day 14, maintained unchanged through Day 28, confirming preservative efficacy.

Procedure:

1. Weigh ingredients of phase A in the main vessel and phase B in another vessel.

2. Heat both phases up to 70° C.

3. Then add phase B in Phase A with continuous mixing.

4. Add phase c at 40° C and mix it well.

Appearance: Milky White Cream

pH: 5.5

Challenge test results:

Inference: In the tested under eye cream formulation, Saliguard LAG delivered rapid, broad spectrum antimicrobial protection, achieving >5 log reductions for E.coli, P.aeruginosa, S.aureus, and C.albicans, and >4.6 log for A.niger by Day 14. All reductions were maintained through Day 28, confirming preservative efficacy.

Comparative Minimum inhibitory Concentration (MIC) results of Saliguard LAG vs Other Preservatives

Inference: Saliguard LAG showed good MIC results across all tested organisms — S.aureus (0.5%), S.epidermidis (0.5%), E.coli (0.5%), P.aeruginosa (0.3%), C.albicans (0.3%), and A.brasiliensis (0.3%). This narrow, low range indicates strong and uniform antimicrobial activity against both bacteria and fungi, making it the reliable broad spectrum preservative in the panel.