Barcelona, April 2024.- Vytrus Biotech, the company specialized in active ingredients derived from plant stem cells for the cosmetic industry, has recently launched its latest biotech active BAOLIFT™ - Your Skin Workout - shortlisted at the Innovation Awards of in-cosmetics Global 2024.
Vytrus has created a 100% natural ingredient that activates the molecular mechanisms of exercise in the skin, improving muscle tone for a lifted skin appearance. This innovative product has been selected amongst the few nominees for the Innovation Awards at in-cosmetics Global 2024, the premier global event for personal care ingredients.
Leveraging advanced plant biotechnology, BAOLIFT™ is a pioneering a new approach to skincare by simulating a fitness regimen at a cellular level, enhancing skin's molecular mechanisms to deliver an efficient V-lifting effect and a rejuvenated appearance. By mirroring the benefits of a physical workout, BAOLIFT™ targets the enhancement of skin resilience and vitality, offering users a path to 'Fit-Skin' through a unique cosmetic solution.
The Workout Factor: a new biological approach in the skin well-ageing
Exercise transforms our bodies improving muscle tone and enhances the physical performance and our well-being as we age. Imagine if similar benefits could be achieved for your skin, solely through cosmetics.
Vytrus has developed a pioneering approach to skincare by mimicking a physical exercise for the facial skin, based on understanding the coordinated exercise response involving the exercise secretome: the Workout Factor. This is characterized as the key axis to harness the biochemistry of exercise and help simultaneously stimulate epidermal and muscular workout factors, promoting enhanced communication through the Skin-Fascia-Muscle axis. This new biological axis is a bidirectional communication network where the skin cells activate muscle cells, which in turn transfer exercise benefits to the skin through the Fascia (the interchanger), as shown in Fig. 1 below:
Fig. 1: The new biological Skin-Fascia-Muscle axis.
The secret behind a ‘Fit-Skin’: the Exerkines
The biotech company introduces the new ‘Fit-Skin’ concept, unveiling the secret of how physical exercise revitalizes not just the body but also your facial skin. At the core of a ‘Fit Skin’ lie the exerkines, beneficial molecules released during physical activity. Vytrus has identified key exerkines essential for skin rejuvenation, highlighting their roles as extracellular messengers that enhance skin and muscle communication, as well as standing out for its ability to amplify exercise effects, significantly improving skin appearance and resilience.
BAOLIFT™ harnesses these discoveries by mimicking the effects of exercise through the bidirectional network of the Skin-Fascia-Muscle axis. This advanced approach engages both skin and muscle cells with exerkines, delivering exercise-like benefits directly to the skin.
A proven efficacy through clinical studies
Firstly, a clinical assay with a mature panel was carried out by Vytrus Biotech to evaluate the well-ageing effect of the active in the improvement of wrinkles’ appearance, hydration and luminosity of the facial skin.
Volunteers showed a dry skin and clinical evidence of cutaneous aging. The new active BAOLIFT™ was able to achieve great results at 14 and 28 days in the 3 markers (wrinkle reduction and moisturization and radiance increase), thanks to the activation of the exercise in the skin and muscle cells (Fig. 2).
Fig. 2: Pictures of the improvement of general appearance of volunteers after applying Baolift™.
In a second assay, Vytrus evaluated the efficacy of BAOLIFT™ to show a tensor (anti-sagging) and anti-gravity effect on the facial skin to provide an overall V-Lifting effect while increasing the firmness and elasticity of the skin up to 13% and 12% at 28 days.
In this clinical test, a weight was used to exert a known force on the cheek to simulate the effect of gravity on sagging skin. Measured the distance between the line passing through the external corner of the eye and ear and the point of application of the weight is measured. BAOLIFT™ demonstrates its protective effect of a gravity-induced deformation, sustained over time, improving facial skin strength, therefore supporting a greater volume of weight (Fig. 3).
Fig. 3: Progressive improvement of skin reshaping (antigravity effect on face contour) of volunteers after applying Baolift™.
Finally, Vytrus carried out a third clinical test on aged volunteers with loss of elasticity, skin sagging and bags under the eyes.
BAOLIFT™ induced a statistically significant reduction in eye bag volume of up to 12.5% at T28 and 30% at T56. In the context of the Primos CR skin profilometry used as clinical method, the color shift transitioning towards red over the 28-day period indicates a reduction in under-eye bag volume (Fig. 4).
Fig. 4: Progressive improvement of skin reshaping (antigravity effect on face contour) of volunteers after applying BAOLIFT™.
Thanks to the activation of the tissue with all its internal layers (the Skin-Fascia-Muscle axis), there is better circulation of facial fluids and a significant reduction in eye bags. Vytrus Biotech proposes the new concept of a Fit-Skin that does not accumulate fat or fluids and it is observed that the improvement is consistent and sustained over time.
The story of an innovation inspired by nature
BAOLIFT™ is a 100% natural active ingredient from the stem cells of baobab (Adansonia digitata). Originated in Africa, baobab tree stands out for its mechanical resistance, long life and high nutritional value. Considered as as a superfood in sports and wellbeing due to its substantial calcium and quality protein content.
Vytrus has pioneered a bioinspired cell training to obtain the Plant Workout Factor from baobab stem cells, delivering a potent molecular synergy. The resulting metabolome is extremely rich in exercise biomimetic molecules such as terpenes, polyphenols and high quality proteins, uniquely positioning BAOLIFT™ at the forefront of biotechnological advancements in skincare as the first skin workout.
This active represents a significant leap forward in the integration of biotechnology and fitness-inspired skincare, offering cosmetic formulators new pathways to formulate firming, strengthening and anti-sagging formulations for face, eye contour and body care with a sustainable solution based on plant biotechnology:
• Products for a fit & shaped skin • Formulations to reduce under eye bags • Strengthening & toning formulas to reduce sagging • V-lifting treatments
Vytrus Biotech’s actives are exclusively distributed in India through its esteemed distributor “Nano Tech Chemical Brothers”. For those who are interested in these latest plant biotechnology innovations for cosmetics, please contact either our technical expert from Vytrus (Mr. Guillem Lao at g.lao@vytrus.com) or our distributor Nano Tech Chemical Brothers at enquiry@chemicalbrothers.co.in or call us at +91 90410 60304